As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why. It is increasingly clear, though, that the loss of synapses-the flexible and adaptive relay ...

A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction ...

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

For more than a century, the story of the brain has been told as a tale of neurons, with every thought and memory traced to their electrical chatter. That narrative is now being rewritten as evidence ...

Whether picking up a small object like a pen or coordinating different body parts, the cerebellum in the brain performs essential functions for controlling our movement. Researchers investigated how a ...

Researchers at Leipzig University's Carl Ludwig Institute have discovered that in the cerebral cortex, synaptic signal transmission between brain cells functions very reliably even at low ...

Professor Jaewon Ko’s research team at DGIST, in collaboration with international researchers, identified that the loss of function of the MDGA2 gene induces severe developmental and epileptic encepha ...

Family with sequence similarity 19 member A5 (FAM19A5) is a secretory protein highly expressed in the brain that regulates synapse dynamics through its interaction with leucine-rich repeat-containing ...