Gene expression reveals that different types of human cell can work as a unit. These cellular modules, found in several tissues, change during disease. However, suitable computational methods are ...

The scope of human cell type atlases widened considerably today. Formerly, landscapes of individual cell types were largely confined to single organs. But now, thanks to four single-cell RNA ...

Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need ...

Stay up to date on the latest science with Brush Up Summaries. Before the advent of spatial transcriptomic analyses, single-cell RNA sequencing methods largely required that scientists break tissue ...

An international team of researchers reached a major milestone in decoding the human genome by linking genes across all chromosome of many individual people to specific tissues and disease processes.

Nucleic acid extraction from biological samples is inherently difficult to execute consistently across different tissue types. Some tissue matrices are fibrous, contained in protective cell walls, or ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists, ...

The average adult male has around 36 trillion cells in their body, while average adult females have 28 trillion, researchers have found. Unexpectedly, the mass of small cells in our bodies, such as ...

Northwestern University researchers almost three years ago introduced an injectable new therapy, which harnessed fast-moving “dancing molecules,” to repair tissues and reverse paralysis after severe ...

In a recent study published in Immunology, researchers investigated populations of regulatory T cells (Treg), a type of white blood cell, in various tissues. Study: The tissue-resident regulatory T ...