Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

A research team has identified a new mechanism that controls DNA’s ability to replicate—and thereby a cell’s ability to ...

UCSF scientists discover that the spindle, the structure that divides chromosomes equally during mitosis, actually gets stronger when it is stretched.

Every second, millions of cells in your body divide in two. In the space of an hour, they duplicate their DNA and grow a web ...

SAR11 bacteria dominate the world’s oceans by being incredibly efficient, shedding genes to survive in nutrient-poor waters.

If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

Common ocean bacteria struggle to divide when conditions change, reshaping how warming seas affect ecosystems.

Chemists induced a cell-like behavior in molecular assemblies called vesicles. They used a sacrificial chemical fuel to make the vesicles divide into smaller versions of themselves. While this process ...