Targeted protein degradation has opened up a new field of drug discovery with potential to treat previously 'undruggable' diseases. The work means new drugs can be much more accurately targeted at the ...

Scientists have discovered a new way to advance drug discovery and diagnostics by targeting a part of the proteome (the complete set of proteins in an organism) that was previously thought ...

Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein accumulation in neurodegenerative diseases, according to a study published ...