The cerebral cortex, the brain's outermost region responsible for higher cognitive functions, depends on a highly ordered, layered structure. Its proper development requires newly generated neurons to ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Neurodegenerative disease profoundly affects structures and pathways responsible for memory, cognition, and higher-order ...

Duke Health researchers found a relationship between immune response and neurological behavior after studying mice with a specific gene mutation, which exhibited signs of ADHD in response to an ...

To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord. This intricate communication network is built of billions of neurons connected by synapses ...

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...

Researchers discover that the RNA surveillance system NMD and the protein UPF2 are essential for guiding neuronal migration and forming the brain's layered cortex.

As detailed in a Stanford-led study published in Nature, researchers successfully created a replica of a neuronal pathway responsible for pain transmission in a lab dish called an “assembloid.” The ...

Cell adhesion molecules (CAMS), i.e., laminin-1 or N-cadhedrin Adhesion and attractant Allow cells to grow along the surfaces of other cells (such as using pioneering axons for subsequent axons) ...

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin, the fatty sheath that covers nerve cells in the brain and spinal cord. Chronic ...