In a new study, researchers describe a method for pinpointing tumor-specific factors in blood that can elicit a protective immune response in the body and may one day be harnessed to produce an ...

For more than a decade, scientist Stephen Albert Johnston and his team at Arizona State University's Biodesign Institute have pooled their energies into an often scoffed-at, high-risk, high-reward ...

A pan-cancer analysis of MUC family genes as potential biomarkers for immune checkpoint therapy.

In this paper we describe a reversion assay specific for the detection of -2 frameshift mutations occuring within short stretches of alternating GC sequences. We have compared a series of chemical ...

Beijing Zhongke Journal Publising Co. Ltd. This study is led by Professor Kabin Xie (Institute of Huazhong Agricultural University College of Plant Science and Technology, Wuhan, China).

Neoantigens are peptides expressed on cancer cells that are generated from mutated genes, and can potentially be identified as foreign by the body’s immune system, which then triggers an attack ...

SNIPRs (Single-Nucleotide-Specific Programmable Riboregulators) can identify any RNA sequence based on a single nucleotide difference. [Shireen Dooling, Biodesign Institute, ASU] SNIPRs, easy-to-build ...

Cystic fibrosis (CF) is an autosomal recessive disease due to a deleterious mutation in a chloride channel gene (CFTR = CF transmembrane conductance regulator), located on chromosome 7. From a ...

SAN DIEGO--(BUSINESS WIRE)--Turning Point Therapeutics, Inc., a clinical-stage precision oncology company designing and developing novel drugs to address treatment resistance, presented data from four ...

Identifying and classifying gene mutations - which are the permanent changes in a person's DNA genetic code - are critical in better understanding, and with research, eventually treating or preventing ...