Scientists from Duke-NUS Medical School, working with collaborators at Imperial College London and partners in Europe and the United States, have uncovered new insights into how an additional copy of ...

Researchers identified three chromosome 21 genes that are overactive in brain cells of individuals with Down syndrome, and demonstrated partial molecular correction using antisense oligonucleotides.

Research on understanding the effect of extra chromosomes for conditions like Down syndrome typically involves examining what genes play a role in the symptoms of these conditions. However, ...

A research team led by scientists at Queen Mary University of London and University College London (UCL) has found new clues about how the brains of people with Down syndrome develop differently from ...

For Ashley Zambelli, a surprise diagnosis allowed her to have an even more special bond with her children. The Michigan-based mom, 23, recently found out she has Mosaic Down syndrome, a condition in ...

Scientists silenced the extra copy of a chromosome that causes Down syndrome in laboratory stem cells, offering the first evidence that it may be possible to correct the genes responsible for the ...

Scientists at Heidelberg University and the University of Arkansas for Medical Sciences conducted a comparative analysis to propose cellular pathologies in genetic diseases such as Down Syndrome that ...

The research team, led by scientists including Ryo Hashizume, worked with skin cells and induced pluripotent stem cells derived from people with Down syndrome. Rather than altering individual genes, ...

Emma McLean is a 6-year-old girl who loves Taylor Swift, reading books, playing the drums and hanging with her little sister. While Emma has Down syndrome — specifically a rare type called Mosaic Down ...

Research on understanding the effect of extra chromosomes for conditions like Down syndrome typically involves examining what genes play a role in the symptoms of these conditions. However, ...