Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...
Life sciences researchers need a host of tools to develop and test critical disease-treating drugs and therapies, from basic research to final product release. Primary cells, media, and reagents are ...
A new study has identified specific cellular machinery that helps brain cells dispose of toxic proteins associated with Alzheimer’s disease. By screening thousands of genes in lab-grown human neurons, ...
Graphene oxide (orange) can effectively enter yeast cells and reduce the toxicity of harmful protein aggregates (light grey), by promoting disassembly and then degradation of the aggregates.
Lung toxicity and fibrosis are caused by inhaling particles, pathogens, and therapeutics. They can also occur following repeated administration of systemic and oral drugs. Any epithelial damage or ...
Crystalline polymers assembled inside tumor cell lysosomes rupture membranes, release iron, and trigger immune-activating ...
Summary and Introduction Clinical Application—Disease Entities Theoretical Framework for Therapy−The 'Steel Paradigm' Conclusion References Theoretical Framework for Therapy−The 'Steel Paradigm' In ...
Targeting OTULIN has proven to eliminate toxic tau proteins in human neurons for the first time, opening a new avenue for treating dementia.
Morning Overview on MSN
Some brain cells resist dementia and scientists finally cracked the code
Researchers have identified a specific protein complex inside neurons that tags toxic tau fragments for destruction, offering the clearest explanation yet for why certain brain cells survive while ...
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